OGG1 Inhibitor TH5487 Alters OGG1 Chromatin Dynamics and Prevents Incisions
OGG1 Inhibitor TH5487 Alters OGG1 Chromatin Dynamics and Prevents Incisions
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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8-oxoguanine DNA glycosylase (OGG1) is the main DNA glycosylase responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG) from duplex DNA to initiate base excision repair. This glycosylase activity is relevant in many pathological conditions including cancer, inflammation, and neurodegenerative diseases. To have a better understanding of th...
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OGG1 Inhibitor TH5487 Alters OGG1 Chromatin Dynamics and Prevents Incisions
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TN_cdi_doaj_primary_oai_doaj_org_article_59172115c77a4c528f52ecb9ab5f4144
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59172115c77a4c528f52ecb9ab5f4144
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom10111483
