Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated v...
Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Recent advances using CRISPR-Cas9 approaches have dramatically enhanced the ease for genetic manipulation in rodents. Notwithstanding, the methods to deliver nucleic acids into pre-implantation embryos have hardly changed since the original description of mouse transgenesis more than 30 years ago. Here we report a novel strategy to generate genetic...
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Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
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TN_cdi_doaj_primary_oai_doaj_org_article_591a750750ef423ca69ffb9deafcbf61
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_591a750750ef423ca69ffb9deafcbf61
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02706-7
