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Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial...

Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_593d8cbdd12d4eee9bf2368860ac1c9f

Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy

About this item

Full title

Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy

Publisher

England: BioMed Central Ltd

Journal title

Genome medicine, 2023-07, Vol.15 (1), p.53-22, Article 53

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Emerging evidence from mouse models is beginning to elucidate the brain's immune response to tau pathology, but little is known about the nature of this response in humans. In addition, it remains unclear to what extent tau pathology and the local inflammatory response within the brain influence the broader immune system.
To address these questi...

Alternative Titles

Full title

Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_593d8cbdd12d4eee9bf2368860ac1c9f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_593d8cbdd12d4eee9bf2368860ac1c9f

Other Identifiers

ISSN

1756-994X

E-ISSN

1756-994X

DOI

10.1186/s13073-023-01205-3

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