Challenges in Antibody Development against Tn and Sialyl-Tn Antigens
Challenges in Antibody Development against Tn and Sialyl-Tn Antigens
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Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
The carbohydrate antigens Tn and sialyl-Tn (STn) are expressed in most carcinomas and usually absent in healthy tissues. These antigens have been correlated with cancer progression and poor prognosis, and associated with immunosuppressive microenvironment. Presently they are used in clinical trials as therapeutic vaccination, but with limited succe...
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Full title
Challenges in Antibody Development against Tn and Sialyl-Tn Antigens
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_593e181b622e4e04a6f03942ad6d1939
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_593e181b622e4e04a6f03942ad6d1939
Other Identifiers
ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom5031783
