Dual anti-inflammatory activities of COX-2/5-LOX driven by kratom alkaloid extracts in lipopolysacch...
Dual anti-inflammatory activities of COX-2/5-LOX driven by kratom alkaloid extracts in lipopolysaccharide-induced RAW 264.7 cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cyclooxygenase (COX) and lipoxygenase (LOX) enzymes play a pivotal role in producing pro-inflammatory eicosanoids, including prostaglandins (PGs) and leukotrienes (LTs), in the inflammation process. Mitragynine is a primary alkaloid contained in the kratom’s leaves and has been reported to show anti-inflammatory activity by suppressing COX-2 mRNA t...
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Dual anti-inflammatory activities of COX-2/5-LOX driven by kratom alkaloid extracts in lipopolysaccharide-induced RAW 264.7 cells
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TN_cdi_doaj_primary_oai_doaj_org_article_5968136b65bb470599807fa4cf6c4264
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5968136b65bb470599807fa4cf6c4264
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-79229-x
