An L-type calcium channel blocker nimodipine exerts anti-fibrotic effects by attenuating TGF-β1 indu...
An L-type calcium channel blocker nimodipine exerts anti-fibrotic effects by attenuating TGF-β1 induced calcium response in an in vitro model of thyroid eye disease
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Author / Creator
Chen, Qian , Pan, Yuan , Hu, Yunwei , Chen, Guanyu , Chen, Xiaoqing , Xie, Yanyan , Wang, Minzhen , Li, Zhuang , Huang, Jun , Shi, Yuxun , Huang, Haixiang , Zhang, Te , Wang, Mei , Zeng, Peng , Wang, Sha , Chen, Rongxin , Zheng, Yongxin , Zhong, Liuxueying , Yang, Huasheng and Liang, Dan
Publisher
England: BMC
Journal title
Language
English
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Publisher
England: BMC
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Contents
Thyroid eye disease (TED) is a vision-threatening autoimmune disorder. Orbital tissue fibrosis leading to intractable complications remains a troublesome issue in TED management. Exploration of novel therapeutic targets and agents to ameliorate tissue fibrosis is crucial for TED. Recent work suggests that Ca
signaling participates in tissue fibr...
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Full title
An L-type calcium channel blocker nimodipine exerts anti-fibrotic effects by attenuating TGF-β1 induced calcium response in an in vitro model of thyroid eye disease
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TN_cdi_doaj_primary_oai_doaj_org_article_597e35a2da604eb9817ad32909e2b16b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_597e35a2da604eb9817ad32909e2b16b
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ISSN
2326-0254
E-ISSN
2326-0254
DOI
10.1186/s40662-024-00401-5
