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SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure

SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5981a2adfffc45beb35d90f870b7c95f

SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure

About this item

Full title

SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2024-08, Vol.20 (8), p.e1012291

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

SARS-CoV-2 spike protein (SARS-2-S) induced cell–cell fusion in uninfected cells may occur in long COVID-19 syndrome, as circulating SARS-2-S or extracellular vesicles containing SARS-2-S (S-EVs) were found to be prevalent in post-acute sequelae of COVID-19 (PASC) for up to 12 months after diagnosis. Although isolated recombinant SARS-2-S protein h...

Alternative Titles

Full title

SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5981a2adfffc45beb35d90f870b7c95f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5981a2adfffc45beb35d90f870b7c95f

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1012291

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