Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscul...
Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Spinal muscular atrophy (SMA) is the leading genetic cause of infant death. It is caused by mutations/deletions of the survival motor neuron 1 (SMN1) gene and is typified by the loss of spinal cord motor neurons, muscular atrophy, and in severe cases, death. The SMN protein is ubiquitously expressed and various cellular- and tissue-specific functio...
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Full title
Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy
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TN_cdi_doaj_primary_oai_doaj_org_article_599aeb8b985249bcacd6dd2353dd68bb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_599aeb8b985249bcacd6dd2353dd68bb
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ISSN
1741-7015
E-ISSN
1741-7015
DOI
10.1186/1741-7015-10-24
