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STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing P...

STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing P...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59bca93925ae4fc893775d67e7c3a7a8

STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation

About this item

Full title

STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2023-03, Vol.14 (3), p.191-191, Article 191

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pancreatic cancer remains one of the most lethal diseases with a relatively low 5-year survival rate, and gemcitabine-based chemoresistance occurs constantly. Mitochondria, as the power factory in cancer cells, are involved in the process of chemoresistance. The dynamic balance of mitochondria is under the control of mitophagy. Stomatin-like protei...

Alternative Titles

Full title

STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_59bca93925ae4fc893775d67e7c3a7a8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59bca93925ae4fc893775d67e7c3a7a8

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-023-05711-5

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