Expression, Purification and Characterization of a Novel Hybrid Peptide CLP with Excellent Antibacte...
Expression, Purification and Characterization of a Novel Hybrid Peptide CLP with Excellent Antibacterial Activity
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
CLP is a novel hybrid peptide derived from CM4, LL37 and TP5, with significantly reduced hemolytic activity and increased antibacterial activity than parental antimicrobial peptides. To avoid host toxicity and obtain high-level bio-production of CLP, we established a His-tagged SUMO fusion expression system in Escherichia coli. The fusion protein c...
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Full title
Expression, Purification and Characterization of a Novel Hybrid Peptide CLP with Excellent Antibacterial Activity
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TN_cdi_doaj_primary_oai_doaj_org_article_59bd9bf67d9748528491ee29f99cbb7d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59bd9bf67d9748528491ee29f99cbb7d
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26237142
