Log in to save to my catalogue

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59cac3fded2d4f39825e28a5697d2477

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

About this item

Full title

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-03, Vol.13 (1), p.1381-1381, Article 1381

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cellular plasticity contributes to intra-tumoral heterogeneity and phenotype switching, which enable adaptation to metastatic microenvironments and resistance to therapies. Mechanisms underlying tumor cell plasticity remain poorly understood. SOX10, a neural crest lineage transcription factor, is heterogeneously expressed in melanomas. Loss of SOX1...

Alternative Titles

Full title

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_59cac3fded2d4f39825e28a5697d2477

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59cac3fded2d4f39825e28a5697d2477

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-28801-y

How to access this item