Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma
About this item
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Author / Creator
Capparelli, Claudia , Purwin, Timothy J. , Glasheen, McKenna , Caksa, Signe , Tiago, Manoela , Wilski, Nicole , Pomante, Danielle , Rosenbaum, Sheera , Nguyen, Mai Q. , Cai, Weijia , Franco-Barraza, Janusz , Zheng, Richard , Kumar, Gaurav , Chervoneva, Inna , Shimada, Ayako , Rebecca, Vito W. , Snook, Adam E. , Hookim, Kim , Xu, Xiaowei , Cukierman, Edna , Herlyn, Meenhard and Aplin, Andrew E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Cellular plasticity contributes to intra-tumoral heterogeneity and phenotype switching, which enable adaptation to metastatic microenvironments and resistance to therapies. Mechanisms underlying tumor cell plasticity remain poorly understood. SOX10, a neural crest lineage transcription factor, is heterogeneously expressed in melanomas. Loss of SOX1...
Alternative Titles
Full title
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma
Authors, Artists and Contributors
Author / Creator
Purwin, Timothy J.
Glasheen, McKenna
Caksa, Signe
Tiago, Manoela
Wilski, Nicole
Pomante, Danielle
Rosenbaum, Sheera
Nguyen, Mai Q.
Cai, Weijia
Franco-Barraza, Janusz
Zheng, Richard
Kumar, Gaurav
Chervoneva, Inna
Shimada, Ayako
Rebecca, Vito W.
Snook, Adam E.
Hookim, Kim
Xu, Xiaowei
Cukierman, Edna
Herlyn, Meenhard
Aplin, Andrew E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_59cac3fded2d4f39825e28a5697d2477
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59cac3fded2d4f39825e28a5697d2477
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28801-y