Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein transl...
Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
The essential process of protein secretion is achieved by the ubiquitous Sec machinery. In prokaryotes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor-protein SecA, in concert with the proton motive force (PMF). However, the mechanism through which ATP hydrolysis by SecA is coupled to directional movement through SecYE...
Alternative Titles
Full title
Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation
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TN_cdi_doaj_primary_oai_doaj_org_article_59d7786eb5d341c08ab44400f000bb12
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59d7786eb5d341c08ab44400f000bb12
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.15598
