Single‐cell transcriptomics reveals a senescence‐associated IL‐6/CCR6 axis driving radiodermatitis
Single‐cell transcriptomics reveals a senescence‐associated IL‐6/CCR6 axis driving radiodermatitis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Irradiation‐induced alopecia and dermatitis (IRIAD) are two of the most visually recognized complications of radiotherapy, of which the molecular and cellular basis remains largely unclear. By combining scRNA‐seq analysis of whole skin‐derived irradiated cells with genetic ablation and molecular inhibition studies, we show that senescence‐associate...
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Single‐cell transcriptomics reveals a senescence‐associated IL‐6/CCR6 axis driving radiodermatitis
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TN_cdi_doaj_primary_oai_doaj_org_article_5a050c8736134d50b74c2fbb8dbbdcf4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a050c8736134d50b74c2fbb8dbbdcf4
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202115653
