From strain engineering to process development: monoclonal antibody production with an unnatural ami...
From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Expansion of the genetic code is a frequently employed approach for the modification of recombinant protein properties. It involves reassignment of a codon to another, e.g., unnatural, amino acid and requires the action of a pair of orthogonal tRNA and aminoacyl tRNA synthetase modified to recognize only the desired amino acid. This approach was ap...
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Full title
From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris
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TN_cdi_doaj_primary_oai_doaj_org_article_5a05cf744b974540bff7da90dfbf2737
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a05cf744b974540bff7da90dfbf2737
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ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/s12934-022-01882-6
