Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML
Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML
About this item
Full title
Author / Creator
Li, Hongjiao , Wang, Yi , Feng, Shuang , Chang, Kaijing , Yu, Xinwen , Yang, Fenfang , Huang, Haozhe , Wang, Yuanbo , Li, Xiang and Guan, Feng
Publisher
London: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
London: BioMed Central
Subjects
More information
Scope and Contents
Contents
Chemoresistance poses a significant impediment to effective treatment strategies for myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Our previous study unveiled that oncogene TWIST1 interacted with DNA methyltransferase 3a (DNMT3a) to regulate the decitabine (DAC) resistance in MDS/AML. However, the underlying mechanism of TWIST1...
Alternative Titles
Full title
Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5a1b2ef9ca984599a29c15dd73d48436
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a1b2ef9ca984599a29c15dd73d48436
Other Identifiers
ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-023-01278-y
