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Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation...

Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a224979cb0c41f395b0bcaf8cec7b56

Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo

About this item

Full title

Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo

Publisher

United States: Elsevier Inc

Journal title

Molecular therapy. Nucleic acids, 2014-07, Vol.3 (7), p.e173-e173, Article e173

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Self-amplifying replicon RNA (RepRNA) possesses high potential for increasing antigen load within dendritic cells (DCs). The major aim of the present work was to define how RepRNA delivered by biodegradable, chitosan-based nanoparticulate delivery vehicles (nanogel-alginate (NGA)) interacts with DCs, and whether this could lead to translation of th...

Alternative Titles

Full title

Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5a224979cb0c41f395b0bcaf8cec7b56

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a224979cb0c41f395b0bcaf8cec7b56

Other Identifiers

ISSN

2162-2531

E-ISSN

2162-2531

DOI

10.1038/mtna.2014.24

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