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Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism sp...

Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism sp...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a363433d94342f1b30a18bf8aa47e48

Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder

About this item

Full title

Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder

Publisher

England: BioMed Central Ltd

Journal title

Molecular brain, 2020-04, Vol.13 (1), p.54-54, Article 54

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders that are highly heterogeneous in clinical symptoms as well as etiologies. Mutations in
SHANK2
are associated with ASD and accordingly,
Shank2
knockout mouse shows ASD-like behavioral phenotypes, including social deficits. Intriguingly, two lines of
Shank2
kn...

Alternative Titles

Full title

Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5a363433d94342f1b30a18bf8aa47e48

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a363433d94342f1b30a18bf8aa47e48

Other Identifiers

ISSN

1756-6606

E-ISSN

1756-6606

DOI

10.1186/s13041-020-00595-4

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