Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism sp...
Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders that are highly heterogeneous in clinical symptoms as well as etiologies. Mutations in
SHANK2
are associated with ASD and accordingly,
Shank2
knockout mouse shows ASD-like behavioral phenotypes, including social deficits. Intriguingly, two lines of
Shank2
kn...
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Full title
Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder
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TN_cdi_doaj_primary_oai_doaj_org_article_5a363433d94342f1b30a18bf8aa47e48
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a363433d94342f1b30a18bf8aa47e48
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ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/s13041-020-00595-4