Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes
Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Arctigenin (ATG) is a major component of
Fructus Arctii
, a traditional herbal remedy that reduced proteinuria in diabetic patients. However, whether ATG specifically provides renoprotection in DKD is not known. Here we report that ATG administration is sufficient to attenuate proteinuria and podocyte injury in mouse models of diabetes. Trans...
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Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes
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TN_cdi_doaj_primary_oai_doaj_org_article_5a5b2bbb2f2147bf8cd9959dcec76d0d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a5b2bbb2f2147bf8cd9959dcec76d0d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12433-w
