Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses
Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses
About this item
Full title
Author / Creator
Li, Qiuhui , Deng, Qu , Chao, Hsueh-Ping , Liu, Xin , Lu, Yue , Lin, Kevin , Liu, Bigang , Tang, Gregory W. , Zhang, Dingxiao , Tracz, Amanda , Jeter, Collene , Rycaj, Kiera , Calhoun-Davis, Tammy , Huang, Jiaoti , Rubin, Mark A. , Beltran, Himisha , Shen, Jianjun , Chatta, Gurkamal , Puzanov, Igor , Mohler, James L. , Wang, Jianmin , Zhao, Ruizhe , Kirk, Jason , Chen, Xin and Tang, Dean G.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Expression of androgen receptor (AR) in prostate cancer (PCa) is heterogeneous but the functional significance of AR heterogeneity remains unclear. Screening ~200 castration-resistant PCa (CRPC) cores and whole-mount sections (from 89 patients) reveals 3 AR expression patterns: nuclear (nuc-AR), mixed nuclear/cytoplasmic (nuc/cyto-AR), and low/no e...
Alternative Titles
Full title
Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses
Authors, Artists and Contributors
Author / Creator
Deng, Qu
Chao, Hsueh-Ping
Liu, Xin
Lu, Yue
Lin, Kevin
Liu, Bigang
Tang, Gregory W.
Zhang, Dingxiao
Tracz, Amanda
Jeter, Collene
Rycaj, Kiera
Calhoun-Davis, Tammy
Huang, Jiaoti
Rubin, Mark A.
Beltran, Himisha
Shen, Jianjun
Chatta, Gurkamal
Puzanov, Igor
Mohler, James L.
Wang, Jianmin
Zhao, Ruizhe
Kirk, Jason
Chen, Xin
Tang, Dean G.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5a734dbbd52a444ea8aff078384df83d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a734dbbd52a444ea8aff078384df83d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06067-7
