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Microglial ASD-related genes are involved in oligodendrocyte differentiation

Microglial ASD-related genes are involved in oligodendrocyte differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a75f1d6512943af8cd72710d5428d1c

Microglial ASD-related genes are involved in oligodendrocyte differentiation

About this item

Full title

Microglial ASD-related genes are involved in oligodendrocyte differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-09, Vol.11 (1), p.17825-17825, Article 17825

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Autism spectrum disorders (ASD) are associated with mutations of chromodomain-helicase DNA-binding protein 8 (Chd8) and tuberous sclerosis complex 2 (Tsc2). Although these ASD-related genes are detected in glial cells such as microglia, the effect of Chd8 or Tsc2 deficiency on microglial functions and microglia-mediated brain development remains un...

Alternative Titles

Full title

Microglial ASD-related genes are involved in oligodendrocyte differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5a75f1d6512943af8cd72710d5428d1c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a75f1d6512943af8cd72710d5428d1c

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-97257-9

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