Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebr...
Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebrafish mutants of Alzheimer's disease risk genes
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Publisher
England: eLife Sciences Publications, Ltd
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Language
English
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England: eLife Sciences Publications, Ltd
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By exposing genes associated with disease, genomic studies provide hundreds of starting points that should lead to druggable processes. However, our ability to systematically translate these genomic findings into biological pathways remains limited. Here, we combine rapid loss-of-function mutagenesis of Alzheimer's risk genes and behavioural pharma...
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Full title
Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebrafish mutants of Alzheimer's disease risk genes
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TN_cdi_doaj_primary_oai_doaj_org_article_5abfb8a74ca64cfe903f83ef1e8adf24
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5abfb8a74ca64cfe903f83ef1e8adf24
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.96839
