Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment...
Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Hepatoblastoma is a rare pediatric liver malignancy usually treated with surgery and chemotherapy. To explore new treatment options for hepatoblastoma, drug screening was performed using six cell models established from aggressive hepatoblastoma tumors and healthy pediatric primary hepatocytes. Of the 527 screened compounds, 98 demonstrated cancer-...
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Full title
Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_5ac5578eeef4411f9cfd2f356a013c05
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ac5578eeef4411f9cfd2f356a013c05
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ISSN
2397-768X
E-ISSN
2397-768X
DOI
10.1038/s41698-025-00915-8
