The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuit...
The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry
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Author / Creator
Liu, Xujun , Si, Wenzhe , He, Lin , Yang, Jianguo , Peng, Yani , Ren, Jie , Liu, Xiaoping , Jin, Tong , Yu, Huajing , Zhang, Zihan , Cheng, Xiao , Zhang, Wenting , Xia, Lu , Huang, Yunchao , Wang, Yue , Liu, Shumeng , Shan, Lin , Zhang, Yu , Yang, Xiaohan , Li, Haixia , Liang, Jing , Sun, Luyang and Shang, Yongfeng
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
The scope and variety of the metabolic intermediates from the mitochondrial tricarboxylic acid (TCA) cycle that are engaged in epigenetic regulation of the chromatin function in the nucleus raise an outstanding question about how timely and precise supply/consumption of these metabolites is achieved in the nucleus. We report here the identification...
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Full title
The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry
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TN_cdi_doaj_primary_oai_doaj_org_article_5acff25e3c624ba6b2d4d4b321b45460
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5acff25e3c624ba6b2d4d4b321b45460
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ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-021-00774-2
