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γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5adbc105176d41f49ebebc1453323bb6

γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

About this item

Full title

γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-08, Vol.9 (1), p.3151-13, Article 3151

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

γδ T cells have many known functions, including the regulation of antibody responses. However, how γδ T cells control humoral immunity remains elusive. Here we show that complete Freund’s adjuvant (CFA), but not alum, immunization induces a subpopulation of CXCR5-expressing γδ T cells in the draining lymph nodes. TCRγδ
+
CXCR5
+
cells p...

Alternative Titles

Full title

γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5adbc105176d41f49ebebc1453323bb6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5adbc105176d41f49ebebc1453323bb6

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-05487-9

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