Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b
Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Reciprocal interactions between B and follicular T helper (Tfh) cells orchestrate the germinal center (GC) reaction, a hallmark of humoral immunity. Abnormal GC responses could lead to the production of pathogenic autoantibodies and the development of autoimmunity. Here we show that miR-146a controls GC responses by targeting multiple CD40 signalin...
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Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b
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TN_cdi_doaj_primary_oai_doaj_org_article_5b06837f8ef2466591810930fcb8fa03
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b06837f8ef2466591810930fcb8fa03
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05196-3