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Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b14d100d8134e01bd5d91d6962c2b54

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

About this item

Full title

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

Publisher

Cambridge: eLife Sciences Publications Ltd

Journal title

eLife, 2023-09, Vol.12

Language

English

Formats

Publication information

Publisher

Cambridge: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Tomosyn is a large, non-canonical SNARE protein proposed to act as an inhibitor of SNARE complex formation in the exocytosis of secretory vesicles. In the brain, tomosyn inhibits the fusion of synaptic vesicles (SVs), whereas its role in the fusion of neuropeptide-containing dense core vesicles (DCVs) is unknown. Here, we addressed this question us...

Alternative Titles

Full title

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5b14d100d8134e01bd5d91d6962c2b54

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b14d100d8134e01bd5d91d6962c2b54

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.85561

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