Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasi...
Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasing mitochondrial respiration
About this item
Full title
Author / Creator
Feng, Juan , Lü, Silin , Ding, Yanhong , Zheng, Ming and Wang, Xian
Publisher
Beijing: Higher Education Press
Journal title
Language
English
Formats
Publication information
Publisher
Beijing: Higher Education Press
Subjects
More information
Scope and Contents
Contents
Hyperhomocysteinemia （HHcy） accelerates atherosclero- sis by increasing proliferation and stimulating cytokine secretion in Tcells. However, whether homocysteine （Hcy）- mediated T cell activation is associated with metabolic reprogramming is unclear. Here, our in vivo and in vitro studies showed that Hcy-stimulated splenic T-cell activa- tion in mi...
Alternative Titles
Full title
Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasing mitochondrial respiration
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5b51fec012f04b559a551908f661c6f4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b51fec012f04b559a551908f661c6f4
Other Identifiers
ISSN
1674-800X
E-ISSN
1674-8018
DOI
10.1007/s13238-016-0245-x
