Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
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Author / Creator
Nishimura, Haruki , Yoshimura, Mitsuhiro , Shimizu, Makiko , Sanada, Kenya , Sonoda, Satomi , Nishimura, Kazuaki , Baba, Kazuhiko , Ikeda, Naofumi , Motojima, Yasuhito , Maruyama, Takashi , Nonaka, Yuki , Baba, Ryoko , Onaka, Tatsushi , Horishita, Takafumi , Morimoto, Hiroyuki , Yoshida, Yasuhiro , Kawasaki, Makoto , Sakai, Akinori , Muratani, Masafumi , Conway-Campbell, Becky , Lightman, Stafford and Ueta, Yoichi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Oxytocin is involved in pain transmission, although the detailed mechanism is not fully understood. Here, we generate a transgenic rat line that expresses human muscarinic acetylcholine receptors (hM3Dq) and mCherry in oxytocin neurons. We report that clozapine-N-oxide (CNO) treatment of our oxytocin-hM3Dq-mCherry rats exclusively activates oxytoci...
Alternative Titles
Full title
Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
Authors, Artists and Contributors
Author / Creator
Yoshimura, Mitsuhiro
Shimizu, Makiko
Sanada, Kenya
Sonoda, Satomi
Nishimura, Kazuaki
Baba, Kazuhiko
Ikeda, Naofumi
Motojima, Yasuhito
Maruyama, Takashi
Nonaka, Yuki
Baba, Ryoko
Onaka, Tatsushi
Horishita, Takafumi
Morimoto, Hiroyuki
Yoshida, Yasuhiro
Kawasaki, Makoto
Sakai, Akinori
Muratani, Masafumi
Conway-Campbell, Becky
Lightman, Stafford
Ueta, Yoichi
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5b705d17b31d48fe8095a53fc1367b16
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b705d17b31d48fe8095a53fc1367b16
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03879-8
