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BiTE‐Secreting CAR‐γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors

BiTE‐Secreting CAR‐γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b897d184f87470e9c3cc91f25007adc

BiTE‐Secreting CAR‐γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors

About this item

Full title

BiTE‐Secreting CAR‐γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors

Publisher

Germany: John Wiley & Sons, Inc

Journal title

Advanced science, 2023-06, Vol.10 (17), p.e2206856-n/a

Language

English

Formats

Publication information

Publisher

Germany: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

HLA‐G is considered as an immune checkpoint protein and a tumor‐associated antigen. In the previous work, it is reported that CAR‐NK targeting of HLA‐G can be used to treat certain solid tumors. However, the frequent co‐expression of PD‐L1 and HLA‐G) and up‐regulation of PD‐L1 after adoptive immunotherapy may decrease the effectiveness of HLA‐G‐CAR...

Alternative Titles

Full title

BiTE‐Secreting CAR‐γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5b897d184f87470e9c3cc91f25007adc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b897d184f87470e9c3cc91f25007adc

Other Identifiers

ISSN

2198-3844

E-ISSN

2198-3844

DOI

10.1002/advs.202206856

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