T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkp...
T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy
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Author / Creator
Stephen, Bettzy , Hajjar, Joud , Sarda, Shrutii , Duose, Dzifa Yawa , Conroy, Jeffrey M , Morrison, Carl , Alshawa, Anas , Xu, Mingxuan , Zarifa, Abdulrazzak , Patel, Sapna P , Yuan, Ying , Kwiatkowski, Evan , Wang, Linghua , Rodon Ahnert, Jordi , Fu, Siqing , Meric-Bernstam, Funda , Lowman, Geoffrey M , Looney, Timothy and Naing, Aung
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publisher
England: BMJ Publishing Group Ltd
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Contents
BackgroundImmune checkpoint inhibitors have revolutionized cancer treatment. However, they are associated with a unique spectrum of side effects, called immune-related adverse events (irAEs), which can cause significant morbidity and quickly progress to severe or life-threatening events if not treated promptly. Identifying predictive biomarkers for...
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Full title
T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_5bcceeb01b534672b53dae6a7f264aae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5bcceeb01b534672b53dae6a7f264aae
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2023-007236
