Timing the initiation of multiple myeloma
Timing the initiation of multiple myeloma
About this item
Full title
Author / Creator
Rustad, Even H. , Yellapantula, Venkata , Leongamornlert, Daniel , Bolli, Niccolò , Ledergor, Guy , Nadeu, Ferran , Angelopoulos, Nicos , Dawson, Kevin J. , Mitchell, Thomas J. , Osborne, Robert J. , Ziccheddu, Bachisio , Carniti, Cristiana , Montefusco, Vittorio , Corradini, Paolo , Anderson, Kenneth C. , Moreau, Philippe , Papaemmanuil, Elli , Alexandrov, Ludmil B. , Puente, Xose S. , Campo, Elias , Siebert, Reiner , Avet-Loiseau, Herve , Landgren, Ola , Munshi, Nikhil , Campbell, Peter J. and Maura, Francesco
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The evolution and progression of multiple myeloma and its precursors over time is poorly understood. Here, we investigate the landscape and timing of mutational processes shaping multiple myeloma evolution in a large cohort of 89 whole genomes and 973 exomes. We identify eight processes, including a mutational signature caused by exposure to melpha...
Alternative Titles
Full title
Timing the initiation of multiple myeloma
Authors, Artists and Contributors
Author / Creator
Yellapantula, Venkata
Leongamornlert, Daniel
Bolli, Niccolò
Ledergor, Guy
Nadeu, Ferran
Angelopoulos, Nicos
Dawson, Kevin J.
Mitchell, Thomas J.
Osborne, Robert J.
Ziccheddu, Bachisio
Carniti, Cristiana
Montefusco, Vittorio
Corradini, Paolo
Anderson, Kenneth C.
Moreau, Philippe
Papaemmanuil, Elli
Alexandrov, Ludmil B.
Puente, Xose S.
Campo, Elias
Siebert, Reiner
Avet-Loiseau, Herve
Landgren, Ola
Munshi, Nikhil
Campbell, Peter J.
Maura, Francesco
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5bcecbd98cdc4f9fbf76239987880049
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5bcecbd98cdc4f9fbf76239987880049
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15740-9
