Neuronal pentraxin 2 is required for facilitating excitatory synaptic inputs onto spinal neurons inv...
Neuronal pentraxin 2 is required for facilitating excitatory synaptic inputs onto spinal neurons involved in pruriceptive transmission in a model of chronic itch
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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An excitatory neuron subset in the spinal dorsal horn (SDH) that expresses gastrin-releasing peptide receptors (GRPR) is critical for pruriceptive transmission. Here, we show that glutamatergic excitatory inputs onto GRPR
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neurons are facilitated in mouse models of chronic itch. In these models, neuronal pentraxin 2 (NPTX2), an activity-depe...
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Neuronal pentraxin 2 is required for facilitating excitatory synaptic inputs onto spinal neurons involved in pruriceptive transmission in a model of chronic itch
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TN_cdi_doaj_primary_oai_doaj_org_article_5be3c1b4351b4acbaf7b273ffea07805
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5be3c1b4351b4acbaf7b273ffea07805
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30089-x
