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T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector

T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5be4580b01cc47c9a59f64f70f8a2add

T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector

About this item

Full title

T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector

Publisher

London: Nature Publishing Group UK

Journal title

npj vaccines, 2024-06, Vol.9 (1), p.102-14, Article 102

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We recently developed an immuno-oncotherapy against human papillomavirus (HPV)-induced tumors based on a lentiviral vector encoding the Early E6 and E7 oncoproteins of HPV16 and HPV18 genotypes, namely “Lenti-HPV-07”. The robust and long-lasting anti-tumor efficacy of Lenti-HPV-07 is dependent on CD8
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T-cell induction and remodeling of the t...

Alternative Titles

Full title

T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5be4580b01cc47c9a59f64f70f8a2add

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5be4580b01cc47c9a59f64f70f8a2add

Other Identifiers

ISSN

2059-0105

E-ISSN

2059-0105

DOI

10.1038/s41541-024-00894-0

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