FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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The fibroblast growth factor FGF21 was labeled with molecularly defined gold nanoparticles (AuNPs), applied to human adipocytes, and imaged by cryo-electron tomography (cryo-ET). Most AuNPs were in pairs about 80 Å apart, on the outer cell surface. Pairs of AuNPs were also abundant inside the cells in clathrin-coated vesicles and endosomes. AuNPs w...
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FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
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TN_cdi_doaj_primary_oai_doaj_org_article_5be575a83d7a4a18a3a1215ed7dd32df
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5be575a83d7a4a18a3a1215ed7dd32df
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.43146
