Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive f...
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
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Author / Creator
Hagenaars, Saskia P. , Liewald, David C. M. , Ahola-Olli, Ari V. , Barnes, Catriona L. K. , Bertram, Lars , Bis, Joshua C. , Burdick, Katherine E. , Christoforou, Andrea , Espeseth, Thomas , Giakoumaki, Stella , Giddaluru, Sudheer , Gustavson, Daniel E. , Lahti, Jari , Leber, Markus , Melle, Ingrid , Oldmeadow, Christopher , Reynolds, Chandra A. , Scholz, Markus , Smith, Jennifer A. , Smith, Albert V. , Thalamuthu, Anbupalam , Trompet, Stella , van der Lee, Sven J. , Ware, Erin B. , Yang, Jingyun , Ames, David , Armstrong, Nicola J. , Assareh, Amelia A. , Böhmer, Anne C. , Campbell, Harry , Cannon, Tyrone D. , Corley, Janie , Cox, Simon R. , Dale, Anders M. , Dick, Danielle , Evangelou, Evangelos , Faul, Jessica D. , Ford, Ian , Gao, He , Giegling, Ina , Gillespie, Nathan A. , Gordon, Scott D. , Gottesman, Rebecca F. , Griswold, Michael E. , Hatzimanolis, Alex , Heiss, Gerardo , Joshi, Peter K. , Kähönen, Mika , Kleineidam, Luca , Kochan, Nicole A. , Le Hellard, Stephanie , Lee, Teresa , Lill, Christina M. , Longstreth, Will T. , Lopez, Oscar L. , Loukola, Anu , Lyytikäinen, Leo-Pekka , Martin, Nicholas G. , Murray, Alison D. , Need, Anna C. , Ollier, William , Polasek, Ozren , Riedel-Heller, Steffi G. , Rose, Richard J. , Rovio, Suvi P. , Schmid, Matthias , Scott, Rodney J. , Scult, Matthew A. , Simino, Jeannette , Straub, Richard E. , Tzoulaki, Ioanna , Uitterlinden, André , Vitart, Veronique , Wagner, Michael , Weinhold, Leonie , Wen, K. Hoyan , Adams, Hieab H. H. , Arking, Dan E. , Chiba-Falek, Ornit , Debette, Stéphanie , Donohoe, Gary , Elliott, Paul , Gill, Michael , Hägg, Sara , Hansell, Narelle K. , Vuoksimaa, Eero , Pendleton, Neil , Porteous, David J. , Rudan, Igor , Dan Rujescu , Schmidt, Reinhold , Schofield, Peter W. , Steen, Vidar M. , Van Duijn, Cornelia M. , Villringer, Arno , Weinberger, Daniel R. , McIntosh, Andrew M. , Gale, Catharine R. , Mosley, Thomas H. and Lencz, Todd
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total
N
= 300,486; age 16–102) and find 148 genome-wide significant independent loci (
P
< 5 × 10
−8
) assoc...
Alternative Titles
Full title
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Authors, Artists and Contributors
Author / Creator
Liewald, David C. M.
Ahola-Olli, Ari V.
Barnes, Catriona L. K.
Bertram, Lars
Bis, Joshua C.
Burdick, Katherine E.
Christoforou, Andrea
Espeseth, Thomas
Giakoumaki, Stella
Giddaluru, Sudheer
Gustavson, Daniel E.
Lahti, Jari
Leber, Markus
Melle, Ingrid
Oldmeadow, Christopher
Reynolds, Chandra A.
Scholz, Markus
Smith, Jennifer A.
Smith, Albert V.
Thalamuthu, Anbupalam
Trompet, Stella
van der Lee, Sven J.
Ware, Erin B.
Yang, Jingyun
Ames, David
Armstrong, Nicola J.
Assareh, Amelia A.
Böhmer, Anne C.
Campbell, Harry
Cannon, Tyrone D.
Corley, Janie
Cox, Simon R.
Dale, Anders M.
Dick, Danielle
Evangelou, Evangelos
Faul, Jessica D.
Ford, Ian
Gao, He
Giegling, Ina
Gillespie, Nathan A.
Gordon, Scott D.
Gottesman, Rebecca F.
Griswold, Michael E.
Hatzimanolis, Alex
Heiss, Gerardo
Joshi, Peter K.
Kähönen, Mika
Kleineidam, Luca
Kochan, Nicole A.
Le Hellard, Stephanie
Lee, Teresa
Lill, Christina M.
Longstreth, Will T.
Lopez, Oscar L.
Loukola, Anu
Lyytikäinen, Leo-Pekka
Martin, Nicholas G.
Murray, Alison D.
Need, Anna C.
Ollier, William
Polasek, Ozren
Riedel-Heller, Steffi G.
Rose, Richard J.
Rovio, Suvi P.
Schmid, Matthias
Scott, Rodney J.
Scult, Matthew A.
Simino, Jeannette
Straub, Richard E.
Tzoulaki, Ioanna
Uitterlinden, André
Vitart, Veronique
Wagner, Michael
Weinhold, Leonie
Wen, K. Hoyan
Adams, Hieab H. H.
Arking, Dan E.
Chiba-Falek, Ornit
Debette, Stéphanie
Donohoe, Gary
Elliott, Paul
Gill, Michael
Hägg, Sara
Hansell, Narelle K.
Vuoksimaa, Eero
Pendleton, Neil
Porteous, David J.
Rudan, Igor
Dan Rujescu
Schmidt, Reinhold
Schofield, Peter W.
Steen, Vidar M.
Van Duijn, Cornelia M.
Villringer, Arno
Weinberger, Daniel R.
McIntosh, Andrew M.
Gale, Catharine R.
Mosley, Thomas H.
Lencz, Todd
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5c177a27f78b4c15af2a914b5490f623
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c177a27f78b4c15af2a914b5490f623
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04362-x
