Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic...
Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Antipsychotic-induced low availability of group II metabotropic glutamate receptors (including mGlu
2
R and mGlu
3
R) in brains of schizophrenia patients may explain the limited efficacy of mGlu
2/3
R ligands in clinical trials. Studies evaluating mGlu
2/3
R levels in well-designed, large postmortem brain cohorts are needed...
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Full title
Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects
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TN_cdi_doaj_primary_oai_doaj_org_article_5c2c7314bce1491f9eb0e77df95c3820
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c2c7314bce1491f9eb0e77df95c3820
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ISSN
2158-3188
E-ISSN
2158-3188
DOI
10.1038/s41398-024-02832-z