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Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic...

Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c2c7314bce1491f9eb0e77df95c3820

Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects

About this item

Full title

Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects

Publisher

London: Nature Publishing Group UK

Journal title

Translational psychiatry, 2024-02, Vol.14 (1), p.113-113, Article 113

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Antipsychotic-induced low availability of group II metabotropic glutamate receptors (including mGlu
2
R and mGlu
3
R) in brains of schizophrenia patients may explain the limited efficacy of mGlu
2/3
R ligands in clinical trials. Studies evaluating mGlu
2/3
R levels in well-designed, large postmortem brain cohorts are needed...

Alternative Titles

Full title

Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5c2c7314bce1491f9eb0e77df95c3820

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c2c7314bce1491f9eb0e77df95c3820

Other Identifiers

ISSN

2158-3188

E-ISSN

2158-3188

DOI

10.1038/s41398-024-02832-z

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