Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K...
Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway
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Author / Creator
Yue, Ziqi , Guan, Xin , Chao, Rui , Huang, Cancan , Li, Dongfang , Yang, Panpan , Liu, Shanshan , Hasegawa, Tomoka , Guo, Jie and Li, Minqi
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Diallyl disulfide (DADs), a natural organic compound, is extracted from garlic and scallion and has anti-tumor effects against various tumors. This study investigated the anti-tumor activity of DADs in human osteosarcoma cells and the mechanisms. MG-63 cells were exposed to DADs (0, 20, 40, 60, 80, and 100 μM) for different lengths of time (24, 48,...
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Full title
Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_5c416a4e06a2427b8a9325e127bc1bb2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c416a4e06a2427b8a9325e127bc1bb2
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24142665
