11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid thera...
11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Despite their efficacy in the treatment of chronic inflammation, the prolonged application of therapeutic glucocorticoids (GCs) is limited by significant systemic side effects including glucocorticoid-induced osteoporosis (GIOP). 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a bi-directional enzyme that primarily activates GCs in vivo, regu...
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Full title
11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_5c44e2a162a740648662dc940e7bc0af
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c44e2a162a740648662dc940e7bc0af
Other Identifiers
ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-019-1972-1
