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Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c8f3813e8b4474bb3fa9ada06482823

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

About this item

Full title

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-07, Vol.14 (1), p.3980-3980, Article 3980

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hepatitis C virus (HCV) is a major global health burden as the leading causative agent of chronic liver disease and hepatocellular carcinoma. While the main antigenic target for HCV-neutralizing antibodies is the membrane-associated E1E2 surface glycoprotein, the development of effective vaccines has been hindered by complications in the biochemica...

Alternative Titles

Full title

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5c8f3813e8b4474bb3fa9ada06482823

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5c8f3813e8b4474bb3fa9ada06482823

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-39659-z

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