Low-dose abiraterone plus Olaparib as a late-line treatment for mCRPC patients without BRCA1/2 mutat...
Low-dose abiraterone plus Olaparib as a late-line treatment for mCRPC patients without BRCA1/2 mutations: a multicenter retrospective pilot study
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Chen, Sijin , Zhong, Dewen , Yu, Chenbo , Cai, Desheng , Wei, Qichen , Yang, Minggen , Li, Tao , Zhu, Qingguo , Ye, Liefu , Wei, Yongbao and Wu, Jinfeng
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although overall survival data are still premature, the PROpel study found radiological progression-free survival (PFS) benefits of abiraterone and olaparib in patients with metastatic castration-resistant prostate cancer (mCRPC). However, for patients who have not been genetically tested or lack BRCA1/2 mutations (BRCAm), this combination therapy...
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Low-dose abiraterone plus Olaparib as a late-line treatment for mCRPC patients without BRCA1/2 mutations: a multicenter retrospective pilot study
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TN_cdi_doaj_primary_oai_doaj_org_article_5ca27f5ab8044e2fb1dc37c979b5226b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ca27f5ab8044e2fb1dc37c979b5226b
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-70398-3