Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multip...
Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Although current chemotherapy using bortezomib (Velcade) against multiple myeloma in adults has achieved significant responses and even remission, a majority of patients will develop acquired resistance to bortezomib. Increased thioredoxin level has been reported to be associated with carcinogenesis; however, the role of thioredoxin in bortezomib d...
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Full title
Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma
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TN_cdi_doaj_primary_oai_doaj_org_article_5cb621da36eb4798a5c436e9966e2213
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5cb621da36eb4798a5c436e9966e2213
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-018-0575-7
