Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining
Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The mutational mechanisms underlying recurrent deletions in clonal hematopoiesis are not entirely clear. In the current study we inspect the genomic regions around recurrent deletions in myeloid malignancies, and identify microhomology-based signatures in
CALR
,
ASXL1
and
SRSF2
loci. We demonstrate that these deletions are the res...
Alternative Titles
Full title
Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5cd49203803b4c6e921be0f40f64c457
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5cd49203803b4c6e921be0f40f64c457
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22803-y
