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Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in...

Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5cd67ecf2c3349869c709be0de116844

Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients

About this item

Full title

Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2019-11, Vol.12 (11)

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterized by cardiac hypertrophy with diastolic dysfunction. Gene mutations causing HCM have been found in about half of the patients, while the genetic etiology and pathogenesis remain unknown for many cases of HCM. To identify novel mechanisms underlying HCM pathogenesis, we generated...

Alternative Titles

Full title

Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5cd67ecf2c3349869c709be0de116844

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5cd67ecf2c3349869c709be0de116844

Other Identifiers

ISSN

1754-8403,1754-8411

E-ISSN

1754-8411

DOI

10.1242/dmm.041103

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