The Good, the Bad, and the Ugly: in search of gold standards for assessing functional genetic screen...
The Good, the Bad, and the Ugly: in search of gold standards for assessing functional genetic screen quality
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Variable screen quality, off‐target effects, and unclear false discovery rates often hamper large‐scale functional genomic screens in mammalian cells. Hart
et al
(2014) introduce gold standard reference sets of essential and non‐essential genes, aiming at standardizing the analysis of genome‐wide screens. This work provides a framework to com...
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The Good, the Bad, and the Ugly: in search of gold standards for assessing functional genetic screen quality
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TN_cdi_doaj_primary_oai_doaj_org_article_5d26379b72464f28a3e38ba8a315e461
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d26379b72464f28a3e38ba8a315e461
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20145372
