Shikonin inhibits cancer cell cycling by targeting Cdc25s
Shikonin inhibits cancer cell cycling by targeting Cdc25s
About this item
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Author / Creator
Zhang, Shoude , Gao, Qiang , Li, Wei , Zhu, Luwei , Shang, Qianhan , Feng, Shuo , Jia, Junmei , Jia, Qiangqiang , Shen, Shuo and Su, Zhanhai
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Shikonin, a natural naphthoquinone, is abundant in Chinese herb medicine Zicao (purple gromwell) and has a wide range of biological activities, especially for cancer. Shikonin and its analogues have been reported to induce cell-cycle arrest, but target information is still unclear. We hypothesized that shikonin, with a structure similar to that of...
Alternative Titles
Full title
Shikonin inhibits cancer cell cycling by targeting Cdc25s
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5d27a722fbb04fa880098f6e902d49bf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d27a722fbb04fa880098f6e902d49bf
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-018-5220-x
