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Delayed generation of functional virus-specific circulating T follicular helper cells correlates wit...

Delayed generation of functional virus-specific circulating T follicular helper cells correlates wit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d37811980464becbf0604481a523bb4

Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

About this item

Full title

Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-04, Vol.14 (1), p.2164-14, Article 2164

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Effective humoral immune responses require well-orchestrated B and T follicular helper (Tfh) cell interactions. Whether these interactions are impaired and associated with COVID-19 disease severity is unclear. Here, longitudinal blood samples across COVID-19 disease severity are analysed. We find that during acute infection SARS-CoV-2-specific circ...

Alternative Titles

Full title

Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5d37811980464becbf0604481a523bb4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d37811980464becbf0604481a523bb4

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-37835-9