Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation
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Author / Creator
Xin, Jingxue , Zhang, Hui , He, Yaoxi , Duren, Zhana , Bai, Caijuan , Chen, Lang , Luo, Xin , Yan, Dong-Sheng , Zhang, Chaoyu , Zhu, Xiang , Yuan, Qiuyue , Feng, Zhanying , Cui, Chaoying , Qi, Xuebin , Ouzhuluobu , Wong, Wing Hung , Wang, Yong and Su, Bing
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
High-altitude adaptation of Tibetans represents a remarkable case of natural selection during recent human evolution. Previous genome-wide scans found many non-coding variants under selection, suggesting a pressing need to understand the functional role of non-coding regulatory elements (REs). Here, we generate time courses of paired ATAC-seq and R...
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Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation
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TN_cdi_doaj_primary_oai_doaj_org_article_5d727e2e509d4204b777b2789c0541c6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d727e2e509d4204b777b2789c0541c6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18638-8