A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversit...
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control
About this item
Full title
Author / Creator
Bartha, István , Carlson, Jonathan M , Brumme, Chanson J , McLaren, Paul J , Brumme, Zabrina L , John, Mina , Haas, David W , Martinez-Picado, Javier , Dalmau, Judith , López-Galíndez, Cecilio , Casado, Concepción , Rauch, Andri , Günthard, Huldrych F , Bernasconi, Enos , Vernazza, Pietro , Klimkait, Thomas , Yerly, Sabine , O'Brien, Stephen J , Listgarten, Jennifer , Pfeifer, Nico , Lippert, Christoph , Fusi, Nicolo , Kutalik, Zoltán , Allen, Todd M , Müller, Viktor , Harrigan, P Richard , Heckerman, David , Telenti, Amalio , Fellay, Jacques and for the HIV Genome-to-Genome Study and the Swiss HIV Cohort Study
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
Subjects
More information
Scope and Contents
Contents
HIV-1 sequence diversity is affected by selection pressures arising from host genomic factors. Using paired human and viral data from 1071 individuals, we ran >3000 genome-wide scans, testing for associations between host DNA polymorphisms, HIV-1 sequence variation and plasma viral load (VL), while considering human and viral population structure....
Alternative Titles
Full title
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control
Authors, Artists and Contributors
Author / Creator
Carlson, Jonathan M
Brumme, Chanson J
McLaren, Paul J
Brumme, Zabrina L
John, Mina
Haas, David W
Martinez-Picado, Javier
Dalmau, Judith
López-Galíndez, Cecilio
Casado, Concepción
Rauch, Andri
Günthard, Huldrych F
Bernasconi, Enos
Vernazza, Pietro
Klimkait, Thomas
Yerly, Sabine
O'Brien, Stephen J
Listgarten, Jennifer
Pfeifer, Nico
Lippert, Christoph
Fusi, Nicolo
Kutalik, Zoltán
Allen, Todd M
Müller, Viktor
Harrigan, P Richard
Heckerman, David
Telenti, Amalio
Fellay, Jacques
for the HIV Genome-to-Genome Study and the Swiss HIV Cohort Study
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5d773a28930442e492f392ab859e9ef9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d773a28930442e492f392ab859e9ef9
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.01123
