MUC1-C intersects chronic inflammation with epigenetic reprogramming by regulating the set1a compass...
MUC1-C intersects chronic inflammation with epigenetic reprogramming by regulating the set1a compass complex in cancer progression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Chronic inflammation promotes epigenetic reprogramming in cancer progression by pathways that remain unclear. The oncogenic MUC1-C protein is activated by the inflammatory NF-κB pathway in cancer cells. There is no known involvement of MUC1-C in regulation of the COMPASS family of H3K4 methyltransferases. We find that MUC1-C regulates (i) bulk H3K4...
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MUC1-C intersects chronic inflammation with epigenetic reprogramming by regulating the set1a compass complex in cancer progression
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TN_cdi_doaj_primary_oai_doaj_org_article_5d8039b4e2e841e5972c3d38760a04a4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d8039b4e2e841e5972c3d38760a04a4
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-023-05395-9
