Multicenter Evaluation of A New Progastrin-releasing Peptide (ProGRP) Immunoassay across Europe and...
Multicenter Evaluation of A New Progastrin-releasing Peptide (ProGRP) Immunoassay across Europe and China
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China: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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Chinese
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China: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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背景 在欧洲和中国进行Elecsys®胃泌素释放肽前体（ProGRP）免疫检测的多中心评估研究。方法 在欧洲的3个中心和中国的2个中心，在肺癌中，通过不精密度、稳定性、方法学比较和鉴别诊断能力来评价该检测法。结果 5个分析物浓度的中间不精密度范围为变异系数：2.2%-6.0%。在不同储存条件下，血浆和血清样本均显示出良好的稳定性。在血浆中Elecsys®和ARCHITECT检测（斜率1.02，截距-2.72 pg/mL）之间表现出良好的相关性。同时，Elecsys®检测在血清和血浆样本之间表现出良好的相关性（斜率0.93，截距2.35 pg/mL；相关系数0.97）。ProGRP作为不受种族、年龄、性别或吸烟史相关影响的检测手段，可鉴别小细胞和非小细胞肺癌（NSCLC）；截断值为84 pg/...
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Multicenter Evaluation of A New Progastrin-releasing Peptide (ProGRP) Immunoassay across Europe and China
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TN_cdi_doaj_primary_oai_doaj_org_article_5d8df451677041339a69b03a224dee64
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d8df451677041339a69b03a224dee64
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ISSN
1009-3419
E-ISSN
1999-6187
DOI
10.3779/j.issn.1009-3419.2017.08.12
